Gene description for ACTB
Gene name actin beta
Gene symbol ACTB
Other names/aliases BKRNS
BNS
BRWS1
CSMH
DDS1
PS1TP5BP1
THC8
Species Homo sapiens
 Experiment description of studies that identified ACTB in Breast cancer cells

1
Experiment ID19
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 16302729   
OrganismHomo sapiens
Experiment descriptionPurification, characterization and biological significance of tumor-derived exosomes.
AuthorsKoga K, Matsumoto K, Akiyoshi T, Kubo M, Yamanaka N, Tasaki A, Nakashima H, Nakamura M, Kuroki S, Tanaka M, Katano M
Journal name ACR
Publication year2005
SampleBreast cancer cells
Sample nameBT-474
MDA-MB-231
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Filtration
Immunobeads(HER2)
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
FACS
EV-TRACK -

2
Experiment ID65
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
Western blotting
PubMed ID 19415654   
OrganismHomo sapiens
Experiment descriptionProteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.
AuthorsStaubach S, Razawi H, Hanisch FG.
Journal name PROTEOMICS
Publication year2009
SampleBreast cancer cells
Sample nameMCF-7
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [MALDI TOF]
Western blotting
EV-TRACK -

3
Experiment ID575
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameBT549
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

4
Experiment ID576
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameHS 578T
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

5
Experiment ID577
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameMCF7
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

6
Experiment ID578
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

7
Experiment ID886
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25102470   
OrganismHomo sapiens
Experiment descriptionExamination of the specificity of tumor cell derived exosomes with tumor cells in vitro
AuthorsSmyth TJ, Redzic JS, Graner MW, Anchordoquy TJ.
Journal name Biochim Biophys Acta
Publication year2014
SampleBreast cancer cells
Sample nameMCF-7
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.10-1.20 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140013: EV-METRIC:56%

8
Experiment ID1255
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24468161   
OrganismHomo sapiens
Experiment descriptionMolecular characterization of exosome-like vesicles from breast cancer cells.
AuthorsKruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R.
Journal name BMC Cancer.
Publication year2014
SampleBreast cancer cells
Sample nameMDA-MB231
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
RT-PCR
Western blotting
EV-TRACK EV140357: EV-METRIC:22%

9
Experiment ID1018
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 22399603   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosome-like vesicles derived from breast cancer cells.
AuthorsPalazzolo G, Albanese NN, DI Cara G, Gygax D, Vittorelli ML, Pucci-Minafra I.
Journal name Anticancer Res
Publication year2012
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV120036: EV-METRIC:44%

10
Experiment ID1028
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 26378940   
OrganismHomo sapiens
Experiment descriptionRedefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis.
AuthorsClark DJ, Fondrie WE, Liao Z, Hanson PI, Fulton A, Mao L, Yang AJ.
Journal name Anal Chem.
Publication year2015
SampleBreast cancer cells
Sample nameSKBR3B - 10 K pellet
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV150004: EV-METRIC:67%, 38%

11
Experiment ID1568
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33738083   
OrganismHomo sapiens
Experiment descriptionBioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases
AuthorsLim GT, You DG, Han HS, Lee H, Shin S, Oh BH, Kumar EKP, Um W, Kim CH, Han S, Lee S, Lim S, Yoon HY, Kim K, Kwon IC, Jo DG, Cho YW, Park JH
Journal name J Extracell Vesicles
Publication year2021
SampleBreast cancer cells
Sample nameMDA‐MB‐231
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immunofluorescence
Flow cytomtery
EV-TRACK -

12
Experiment ID1569
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33738083   
OrganismHomo sapiens
Experiment descriptionBioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases
AuthorsLim GT, You DG, Han HS, Lee H, Shin S, Oh BH, Kumar EKP, Um W, Kim CH, Han S, Lee S, Lim S, Yoon HY, Kim K, Kwon IC, Jo DG, Cho YW, Park JH
Journal name J Extracell Vesicles
Publication year2021
SampleBreast cancer cells
Sample nameMDA‐MB‐231
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immunofluorescence
Flow cytomtery
EV-TRACK -

13
Experiment ID1664
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34108659   
OrganismHomo sapiens
Experiment descriptionQuantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
AuthorsKugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R.
Journal name Nat Cell Biol
Publication year2021
SampleBreast cancer cells
Sample nameMCF7
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
mRNA
Methods used in the studyRT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
EV-TRACK -

14
Experiment ID1937
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36193887   
OrganismHomo sapiens
Experiment descriptionMachine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity
AuthorsRamos EK, Tsai CF, Jia Y, Cao Y, Manu M, Taftaf R, Hoffmann AD, El-Shennawy L, Gritsenko MA, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Liu X, Patel P, Wray B, Zhang Y, Zhang S, Moore RJ, Mathews JV, Schipma MJ, Liu T, Tokars VL, Cristofanilli M, Shi T, Shen Y, Dashzeveg NK, Liu H.
Journal name Elife
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

15
Experiment ID1938
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36193887   
OrganismHomo sapiens
Experiment descriptionMachine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity
AuthorsRamos EK, Tsai CF, Jia Y, Cao Y, Manu M, Taftaf R, Hoffmann AD, El-Shennawy L, Gritsenko MA, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Liu X, Patel P, Wray B, Zhang Y, Zhang S, Moore RJ, Mathews JV, Schipma MJ, Liu T, Tokars VL, Cristofanilli M, Shi T, Shen Y, Dashzeveg NK, Liu H.
Journal name Elife
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

16
Experiment ID1939
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36193887   
OrganismHomo sapiens
Experiment descriptionMachine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity
AuthorsRamos EK, Tsai CF, Jia Y, Cao Y, Manu M, Taftaf R, Hoffmann AD, El-Shennawy L, Gritsenko MA, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Liu X, Patel P, Wray B, Zhang Y, Zhang S, Moore RJ, Mathews JV, Schipma MJ, Liu T, Tokars VL, Cristofanilli M, Shi T, Shen Y, Dashzeveg NK, Liu H.
Journal name Elife
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

17
Experiment ID3287
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

18
Experiment ID3288
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

19
Experiment ID3289
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 1
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density1.05 g/mL
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

20
Experiment ID3290
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 5
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

21
Experiment ID3291
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 6
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

22
Experiment ID3292
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 7
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

23
Experiment ID3293
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 8
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

24
Experiment ID3294
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 9
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

25
Experiment ID3298
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 5
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

26
Experiment ID3299
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 6
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

27
Experiment ID3300
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 7
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

28
Experiment ID3301
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 8
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

29
Experiment ID3302
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231 - Fraction 9
Isolation/purification methodsDifferential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

30
Experiment ID3303
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

31
Experiment ID3304
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32848136   
OrganismHomo sapiens
Experiment descriptionITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
AuthorsFuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S.
Journal name Nat Commun
Publication year2020
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

32
Experiment ID1759
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameLM2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

33
Experiment ID1759
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameLM2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

34
Experiment ID1759
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameLM2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

35
Experiment ID1759
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameLM2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

36
Experiment ID1761
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameLM2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

37
Experiment ID1761
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameLM2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

38
Experiment ID1761
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameLM2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

39
Experiment ID1761
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameLM2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

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